Objective: To summarize the use of Chinese herbal medicines (CHM) for the treatment of hand-foot-and-mouth disease (HFMD) in children and to provide high-level evidence for clinical decision-making. Methods: We conducted an overview of systematic reviews (SRs). Two English-language and four Chinese-language electronic databases were searched from inception to March 31. 2018. https://herbsdailyes.shop/product-category/plant-protein/